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FLASH GENE

Symbol

SLC25A42

contributors: mct - updated : 06-11-2020

HGNC name	solute carrier family 25, member 42
HGNC id	28380

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19p13.11      Physical location : 19.174.802 - 19.223.704
Synonym symbol(s)	FLJ54826, MGC26694, MECREN

DNA

TYPE	functioning gene
STRUCTURE	49.04 kb     8 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_178526 8 - 3160 NP_848621 - 318 - 2013 23266187 NM_001321544 8 - 3198 NP_001308473 - 318 - 2013 23266187

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland       highly Lymphoid/Immune lymph node       highly Nervous brain forebrain cerebral cortex   highly Olfactory (smell) olfactory bulb       highly Reproductive female system uterus cervix   highly Urinary kidney       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

three solcar repeats

HOMOLOGY

Homologene

FAMILY

mitochondrial carrier family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,inner
	intracellular,cytoplasm,organelle,membrane
	intracellular,nucleus

basic FUNCTION	imports coenzyme A into mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and ADP (Fiermonte 2009)
	might likely exchange mitochondrial dephosphoCoA (dPCoA) with cytosolic ADP, allowing coenzyme A (CoA) to be produced both in the matrix by coenzyme A synthase (COASY) and in the cytosol by the monofunctional dPCoA kinase

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	nucleotide,
	ADP binding

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS