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FLASH GENE
Symbol SLC25A40 contributors: mct - updated : 14-01-2016
HGNC name solute carrier family 25, member 40
HGNC id 29680
Location 7q21.12      Physical location : 87.463.813 - 87.505.692
Synonym name mitochondrial carrier family protein
Synonym symbol(s) MCFP
DNA
TYPE functioning gene
STRUCTURE 42.81 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 3152 - 338 - 2013 24268658
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   highly
Lymphoid/Immunelymph node   highly
Nervousbrain   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
three solcar repeats
HOMOLOGY
intraspecies homolog to SLC25A39
Homologene
FAMILY mitochondrial carrier family
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
intracellular,cytoplasm,organelle,membrane
text
  • localizes to the mitochondria
    • basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional       loss of function
    of SLC25A39 and SLC25A40 might sensitize the cellular environment to toxic insults, predisposing them to neuronal defects
    Susceptibility to high triglyceride (TG) level
    Variant & Polymorphism SNP increasing the triglyceride (TG) level
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS