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FLASH GENE

Symbol

NCK1

contributors: mct - updated : 13-04-2017

HGNC name	NCK adaptor protein 1
HGNC id	7664

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional         NCK1 silencing in pancreatic beta cells promotes EIF2AK3 activation and signaling to protect beta cells against pathological stresses

Susceptibility

to diabetic nephropathy (DN) in type 1 diabetes mellitus

Variant & Polymorphism other	variant increasing the risk of diabetic nephropathy (DN) in type 1 diabetes mellitus

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS