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FLASH GENE
Symbol HPCAL1 contributors: npt/ - updated : 21-04-2008
HGNC name hippocalcin-like 1
HGNC id 5145
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine hippocalcin like-1
homolog to rattus hippocalcin like-1
homolog to Drosophila Nca
homolog to C.elegans ncs-3
intraspecies homolog to hippocalcin
Homologene
FAMILY
  • neuron-specific calcium-binding proteins family
  • recoverin family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the calcium-dependent regulation of rhodopsin phosphorylation
  • may be of relevance for neuronal signaling in the central nervous system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
  • binding to actin, tubulin, clathrin
  • NRF1 could be a regulatory factor for VSNL1 gene expression and for other visinin-like subfamily members including HPCAL4, HPCAL1, HPCA, and NCALD
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS