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FLASH GENE
Symbol SERPINA6 contributors: - updated : 09-12-2005
HGNC name serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
HGNC id 1540
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 19.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure ( 5'intronic promoter) binded to several nuclear matrix attachment region (MAR)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Respiratorylung    
cell lineage
cell lines hepatoma cells
fluid/secretion plasma
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY member of the serpin superfamily
CATEGORY enzyme , transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • corticosteroid binding globulin
  • serine proteinase inhibitor
  • involved in the regulation of gene activity and chromatin structure
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CBG
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS