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FLASH GENE
Symbol LCE4A contributors: mct - updated : 05-03-2024
HGNC name late cornified envelope 4A
HGNC id 16613
Location 1q21.3      Physical location : 152.681.522 - 152.681.910
Synonym name
  • small proline rich-like (epidermal differentiation complex) 4A
  • late envelope protein 8
    • Synonym symbol(s) LEP8, SPRL4A
    DNA
    TYPE functioning gene
    STRUCTURE 1.27 kb     1 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 388 - 99 - 2005 15854049
    2 - 615 - 99 - 2005 15854049
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • LCE family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • constituent of the epidermal cornified envelope
  • modulate likely barrier activity over the surface, in a manner analogous to that proposed for the well characterized cornified envelope precursors, the small proline-rich protein
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS