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FLASH GENE

Symbol

LCE2C

contributors: mct - updated : 18-10-2022

HGNC name	late cornified envelope 2C
HGNC id	29460

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1q21.3      Physical location : 152.647.770 - 152.649.047
Synonym name	late envelope protein 11
Synonym symbol(s)	LEP11

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
STRUCTURE	1.28 kb     2 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_178429 2 - 614 NP_848516 - 110 - Jackson (2005)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial barrier lining epidermis stratum corneum   Homo sapiens

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

intraspecies

homolog to LCE2D (96.4pc)

Homologene

FAMILY

LCE family

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION

basic FUNCTION	LCE2 proteins are found only in the uppermost granular layer and stratum corneum
	LCE2C, LCE3C have distinct functions in epidermal biology

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS