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FLASH GENE
Symbol KRT24 contributors: mct/npt - updated : 11-06-2024
HGNC name keratin 24
HGNC id 18527
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 mouth   highly
Endocrineparathyroid   highly
Lymphoid/Immunespleen   highly
 thymus    
Reproductivefemale systemplacenta  highly
Visualeye   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentkeratinocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Krt24 (75.2pc)
homolog to rattus Ka24 (75.3pc)
Homologene
FAMILY
  • intermediate filament family
  • type I keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • epithelial keratins associated with simple/glandular or stratified, non-cornified epithelia
  • KRT24 may be suggested as a potential differentiation marker and anti-proliferative factor in the epidermis 7)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other UV radiation may promote the modulation of KRT24 and MMP9 pterygium-related genes and induce the initiation and progression of ocular pterygium
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to colorectal cancer
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS