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FLASH GENE
Symbol EVI5L contributors: mct - updated : 10-02-2015
HGNC name ecotropic viral integration site 5-like
HGNC id 30464
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • USP6/Bub2/CDC16 (TBC) domain-containing proteins subfamily
    • CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • TBC1D7, and EVI5L, are involved in primary cilia formation
  • having Rab-GAP activity towards RAB10 as well as RAB23, and has been implicated in primary cilia formation
  • TGIF1, TGIF2 regulate ciliogenesis and EVI5L mediates likely at least part of this effect
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • EVI5L interacting with RAB10
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS