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FLASH GENE
Symbol IMP4 contributors: - updated : 07-09-2006
HGNC name IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
HGNC id 30856
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one Brix domain
    • conjugated RiboP
    HOMOLOGY
    interspecies homolog to murine Imp4 (97.3pc)
    homolog to rattus Imp4 (97.9pc)
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • required for the early cleavages during pre-18S ribosomal RNA processing
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP)
  • component of a heterotrimeric complex containing IMP3, IMP4 and KIF20B
    • INTERACTION
    DNA
    RNA binding
    small molecule
    protein interacting with KIF20B
    cell & other
    REGULATION
    Other the formation of the ternary complex of IMP3, IMP4 and MPP10 is required for their association with nucleolar components
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS