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FLASH GENE
Symbol IMP4 contributors: - updated : 07-09-2006
HGNC name IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
HGNC id 30856
DNA
TYPE functioning gene
STRUCTURE 3.00 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
Lymphoid/Immunelymph node    
 spleen    
 tonsils    
Skin/Tegumentskin    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscular    
cell lineage
cell lines
fluid/secretion lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one Brix domain
    • conjugated RiboP
    HOMOLOGY
    interspecies homolog to murine Imp4 (97.3pc)
    homolog to rattus Imp4 (97.9pc)
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • required for the early cleavages during pre-18S ribosomal RNA processing
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP)
  • component of a heterotrimeric complex containing IMP3, IMP4 and KIF20B
    • INTERACTION
    DNA
    RNA binding
    small molecule
    protein interacting with KIF20B
    cell & other
    REGULATION
    Other the formation of the ternary complex of IMP3, IMP4 and MPP10 is required for their association with nucleolar components
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS