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FLASH GENE
Symbol HEXIM2 contributors: np/ - updated : 28-06-2006
HGNC name hexamthylene bis-acetamide inducible 2
HGNC id 28591
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , heteromer , dimer , oligo
HOMOLOGY
Homologene
FAMILY
  • HEXIM family
    • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • transcriptional repressor activity
  • regulator of CCNT1 activity
  • fonctionally and quantitatively compensate the lack of HEXIM1
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of a complex made of CCNT1, 7SK RNA and HEXIM1 or HEXIM2
    • INTERACTION
    DNA
    RNA 7SK RNA binding
    small molecule
    protein
  • binding CCNT1 (positive transcriptional elongation factor b), and having regulated association with CCNT1
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS