Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol FAM57B contributors: mct - updated : 08-04-2015
HGNC name family with sequence similarity 57, member B
HGNC id 25295
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one TLC (TRAM/LAG1/CLN8) domain, that is related to ceramide synthase
    • HOMOLOGY
    interspecies homolog to rattus rgd1308215
    Homologene
    FAMILY FAM57 family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text
  • distributed in the ER and Golgi
    • basic FUNCTION
  • regulates adipogenesis through ceramide synthesis
  • FAM57B interferes with adipogenesis by augmenting ceramide synthesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PPARG-responsive transmembrane gene that is related to obesity
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS