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FLASH GENE

Symbol

MSTO1

contributors: mct - updated : 22-06-2022

HGNC name	misato mitochondrial distribution and morphology regulator 1
HGNC id	29678

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	51.72 kb     14 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

Map	cen - D1S2714 - D1S2777 - MSTO1 - D1S303 - D1S2721 - qter
Authors	UCSC (2009)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_018116 14 - 2422 NP_060586 61.7 570 - 2007 17349998 NM_001350779 14 - 2530 NP_001337708 - 393 - 2007 17349998 NM_001350784 14 - 2567 NP_001337713 - 389 - 2007 17349998 NM_001350785 14 - 3027 NP_001337714 - 389 - 2007 17349998 NM_001350781 14 - 3039 NP_001337710 - 392 - 2007 17349998 NM_001350778 14 - 2589 NP_001337707 - 393 - 2007 17349998 NM_001350789 14 - 2651 NP_001337718 - 373 - 2007 17349998 NM_001350786 14 - 2601 NP_001337715 - 380 - 2007 17349998 NM_001350788 14 - 2589 NP_001337717 - 376 - 2007 17349998 NM_001350782 14 - 2564 NP_001337711 - 392 - 2007 17349998 NM_001350783 14 - 2561 NP_001337712 - 391 - 2007 17349998 NM_001350780 14 - 2638 NP_001337709 - 392 - 2007 17349998 NM_001350776 14 - 2622 NP_001337705 - 515 - 2007 17349998 NM_001350777 14 - 2525 NP_001337706 - 393 - 2007 17349998 NM_001350773 14 - 2537 NP_001337702 - 558 - 2007 17349998 NM_001350787 14 - 2529 NP_001337716 - 378 - 2007 17349998 NM_001350774 14 - 2534 NP_001337703 - 557 - 2007 17349998 NM_001350772 14 - 2467 NP_001337701 - 559 - 2007 17349998 NM_001350775 14 - 2525 NP_001337704 - 554 - 2007 17349998 NM_001256533 14 - 2464 NP_001243462 - 558 - 2007 17349998 NM_001256532 14 - 2497 NP_001243461 - 569 - 2007 17349998

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

PhosphoP

HOMOLOGY

interspecies	homolog to rattus Msto1 (81.9 pc)
	homolog to murine Msto1 (80.1 pc)

Homologene

FAMILY

misato family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,outer
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,cytosolic
text	cytosolic mitochondrial fusion protein

basic FUNCTION	involved in the regulation of mitochondrial distribution and morphology
	involved in protein polymerization
	playing a role in mitochondrial fusion
	likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

MSTO1 interacts with the fusion machinery as a soluble factor at the cytoplasm-mitochondrial outer membrane interface

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

MMYAT

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS