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FLASH GENE
Symbol MSTO1 contributors: mct - updated : 22-06-2022
HGNC name misato mitochondrial distribution and morphology regulator 1
HGNC id 29678
Corresponding disease
MMYAT myopathy, mitochondrial, and ataxia
Location 1q22      Physical location : 155.580.006 - 155.584.757
Genatlas name misato homolog 1
Synonym symbol(s) MST, LST005, FLJ10504, RP11-29H23.3, DKFZp686B1757, DKFZp686I01261, MMYAT
DNA
TYPE functioning gene
STRUCTURE 51.72 kb     14 Exon(s)
MAPPING cloned Y linked N status provisional
Map cen - D1S2714 - D1S2777 - MSTO1 - D1S303 - D1S2721 - qter
Authors UCSC (2009)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 2422 61.7 570 - 2007 17349998
14 - 2530 - 393 - 2007 17349998
14 - 2567 - 389 - 2007 17349998
14 - 3027 - 389 - 2007 17349998
14 - 3039 - 392 - 2007 17349998
14 - 2589 - 393 - 2007 17349998
14 - 2651 - 373 - 2007 17349998
14 - 2601 - 380 - 2007 17349998
14 - 2589 - 376 - 2007 17349998
14 - 2564 - 392 - 2007 17349998
14 - 2561 - 391 - 2007 17349998
14 - 2638 - 392 - 2007 17349998
14 - 2622 - 515 - 2007 17349998
14 - 2525 - 393 - 2007 17349998
14 - 2537 - 558 - 2007 17349998
14 - 2529 - 378 - 2007 17349998
14 - 2534 - 557 - 2007 17349998
14 - 2467 - 559 - 2007 17349998
14 - 2525 - 554 - 2007 17349998
14 - 2464 - 558 - 2007 17349998
14 - 2497 - 569 - 2007 17349998
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
interspecies homolog to rattus Msto1 (81.9 pc)
homolog to murine Msto1 (80.1 pc)
Homologene
FAMILY
  • misato family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,outer
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,cytosolic
    text
  • cytosolic mitochondrial fusion protein
  • basic FUNCTION
  • involved in the regulation of mitochondrial distribution and morphology
  • involved in protein polymerization
  • playing a role in mitochondrial fusion
  • likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • MSTO1 interacts with the fusion machinery as a soluble factor at the cytoplasm-mitochondrial outer membrane interface
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MMYAT
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS