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FLASH GENE

Symbol

HPDL

contributors: mct - updated : 30-09-2020

HGNC name	4-hydroxyphenylpyruvate dioxygenase-like
HGNC id	28242

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

HPDLD , SPG83

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   HPDL were down-regulated in HCC (hepatocellular carcinoma)cell lines through promoter methylation

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	CNV of HPDL is not only related to the patient's prognosis, but also related to gene methylation and expression levels affecting the patient's survival time in breast cancer
Therapy target

ANIMAL & CELL MODELS