basic FUNCTION
| binds to microtubules, localizes on the spindle, acts as a scaffold that binds to both STK38 and MOB2, and synergistically activates STK38 with MOB2  |
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STK3-, FRY-, and MOB2-mediated activation of STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells |
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evolutionarily conserved protein implicated in cell division and morphology  |
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plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis |
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plays a crucial role in PLK1 activation in early mitosis |
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plays a crucial role in spindle pole integrity by promoting PLK1 activity on centrosomes in early mitosis |
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evolutionarily conserved protein that binds to MTs (microtubules) and colocalizes with acetylated MTs in the mitotic spindle  |
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plays a crucial role in promoting the level of MT acetylation in the mitotic spindle by inhibiting the tubulin-deacetylase activity of SIRT2  |