Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PLPPR2 contributors: mct/npt - updated : 07-09-2020
Location 19p13.2      Physical location : -
Genatlas name lipid phosphate phosphatase-related protein type 2
Synonym name plasticity-related gene-4
Synonym symbol(s) PRG-4, FLJ13055, DKFZp761E1121, LPPR2
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 2686 36 343 - Savaskan (2004)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel   moderately
Digestiveintestinesmall intestine  moderately
Endocrineadrenal gland   moderately
 parathyroid   moderately
Lymphoid/Immunespleen   highly
 thymus   highly
Nervousbrain   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connective    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
interspecies ortholog to rattus Prg-4
Homologene
FAMILY
  • lipid phosphate phosphatase (LPP) family
  • PLPPR family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • mediate lipid phosphate phosphatase activity and involved in mechanisms of neuronal plasticity
  • shows dynamic expression regulation during brain development and neuronal excitation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • new functional cooperation between PLPPR family members and discovered for the first time that PLPPRs likely exert their function through forming complex with its family members
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS