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FLASH GENE
Symbol ZNF33A contributors: npt - updated : 02-03-2010
HGNC name zinc finger protein 33A
HGNC id 13096
Location 10p11.1      Physical location : 38.299.577 - 38.348.994
Synonym name
  • zinc finger protein 33a (KOX 31)
  • zinc finger protein 11A
  • zinc finger and ZAK-associated protein with KRAB domain
  • Krueppel-related zinc finger protein, ZNF family
  • Synonym symbol(s) KOX31, ZNF33, FLJ23404, KIAA0065, KOX5, ZZAPK, KOX2, NF11A, ZNF11A
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text
  • member of the paracentric cluster, short arm, with ZNF25, ZNF33A, ZNF37A
  • STRUCTURE 49.42 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    Physical map
    LOC387651 10 similar to Pre-B cell enhancing factor precursor LOC389948 10 similar to MAP kinase-interacting serine/threonine kinase 1; MAP kinase interacting kinase 1 NY-BR-1 10p11.21 breast cancer antigen NY-BR-1 LOC387652 10 similar to hypothetical protein MGC33214 LOC219752 10p11.21 similar to TACC1 protein LOC387653 10 similar to tousled-like kinase 2; serine/threonine kinase; tousled-like kinase ZNF248 10p11.2 zinc finger protein 248 LOC387654 10 LOC387654 BA775A3.1 10p11 KRAB box zinc finger protein pseudogene LOC389949 10 similar to zinc finger protein 11b (KOX 2) ZNF25 10p11.2 zinc finger protein 25 (KOX 19) ZNF33A 10p11.2 zinc finger protein 33a (KOX 31) LOC389950 10 LOC389950 LOC340947 10p11.21 similar to bA508N22.1 (HSPC025) ZNF37A 10p11.2 zinc finger protein 37a (KOX 21) LOC389951 10 similar to Zinc finger protein 37A (Zinc finger protein KOX21) LOC389952 10 similar to KIAA1975 protein LOC158160 10p11.21 hypothetical protein LOC158160 LOC387655 10 similar to bA291L22.2 (similar to CDC10 (cell division cycle 10, S. cerevisiae, homolog)) LOC387656 10 LOC387656 bA291L22.4 10p11 hypothetical pseudogene bA291L22.4 ABCD1P2 10p11 ATP-binding cassette, sub-family D (ALD), member 1, pseudogene 2 LOC387657 10 similar to hypothetical protein LOC387658 10 hypothetical gene supported by AY026352
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 6130 - 811 - -
    5 - 6127 94 810 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymphocyte
    Lymphoid/ImmuneT cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 16 C2H2 type, Krüppel-like domains
  • a KRAB domain at the N terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • may be involved in transcriptional regulation
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS