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FLASH GENE

Symbol

CPNE9

contributors: mct/npt - updated : 30-11-2009

HGNC name	copine family member IX
HGNC id	24336

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine neuroendocrine pituitary       Lymphoid/Immune spleen       predominantly Nervous nerve       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a Ca(2+) and phospholipid-binding domain consisting of two C2 domains
	a core domain in the C-terminal portion that is homologous to the A domain found in certain integrins (Tomsig 2000)

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

copine family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

basic FUNCTION

exhibits Ca(2+) self-association to form higher-order multimers, and Ca(2+)-dependent, phospholipid binding activity with preference for negatively charged phospholipids over neutral phospholipids (Tomsig 2000)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS