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FLASH GENE

Symbol

FAM111B

contributors: mct - updated : 14-01-2014

HGNC name	family with sequence similarity 111, member B
HGNC id	24200

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Corresponding disease	FPTCM hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis
Location	11q12.1      Physical location : 58.874.657 - 58.894.886
Synonym name	cancer associated nucleoprotein
Synonym symbol(s)	CANP

DNA

TYPE	functioning gene
STRUCTURE	20.23 kb     4 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_198947 4 - 3574 NP_945185 - 734 - 2013 24268661 NM_001142703 3 - 3407 NP_001136175 - 704 - 2013 24268661 NM_001142704 2 - 3362 NP_001136176 - 704 - 2013 24268661

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Respiratory respiratory tract trachea       Homo sapiens mRNA Skin/Tegument skin         Homo sapiens mRNA

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal     Homo sapiens mRNA

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

SUBCELLULAR LOCALIZATION

basic FUNCTION

critical gene in the development of fibrosis, which is a key pathological process in many human diseases

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

FPTCM

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS