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FLASH GENE

Symbol

FAM109B

contributors: mct - updated : 18-10-2011

HGNC name	family with sequence similarity 109, member B
HGNC id	27161

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001002034 3 - 2369 - 259 - 2010 20133602

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

homomer , heteromer , dimer

HOMOLOGY

Homologene

FAMILY

CATEGORY

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,Golgi
	intracellular,cytoplasm,organelle,endosome
text	localize to early and recycling endosomes and the trans-Golgi network (TGN)

basic FUNCTION

key player in endocytic trafficking

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

form homo- and heterodimers

INTERACTION

DNA

RNA

small molecule

protein	interact with the ASH-RhoGAP-like (ASPM-SPD-2-Hydin homology and Rho-GTPase Activating Domain-like) domain of OCRL
	OCRL-binding protein, that also bind the related 5-phosphatase INPP5B

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS