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FLASH GENE

Symbol

NPPC

contributors: mct - updated : 16-01-2024

HGNC name	natriuretic peptide precursor C
HGNC id	7941

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SSSH

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed immunology inflammatory   enhanced NPPC signalling may prevent growth retardation and protect cartilage in patients with inflammatory joint disease reproduction fertility   NPPC supplementation constitutes an alternative therapeutic approach for advanced maternal age-related oocyte deterioration and may improve the overall success rates of clinically assisted reproduction in older women

ANIMAL & CELL MODELS

spermatozoa from Npr2 mutant mice were not attracted by Nppc, preventing fertilization in vivo