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FLASH GENE
Symbol DOK6 contributors: - updated : 03-04-2006
HGNC name docking protein 6
HGNC id 28301
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a IRS-type PTB domain mediating receptor interaction
  • a PH domain
    • HOMOLOGY
    Homologene
    FAMILY DOK family, type B subfamily
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • promotes Ret- mediated neurite growth
  • may have a role in brain development and/or
    • maintainance
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts via its PTB domain with phosphorylated RET
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism other aphidicolin-inducible fragile site
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS