Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

NFATC2

contributors: mct/npt/pgu - updated : 25-04-2012

HGNC name	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
HGNC id	7776

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function not only protects the heart from pathological hypertrophy but also efficiently counteracts myocardial functional deterioration following biomechanical stress

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular aquired heart failure targeting either NFATc2 activation or its immediate downstream target genes provide a suitable approach for future drug design to treat forms of pathological cardiac hypertrophy and heart failure cancer digestive pancreas inactivation of oncogenic NFATc2 might be an attractive strategy in treatment of pancreatic cancer

ANIMAL & CELL MODELS