basic FUNCTION
| acting as an oxidoreductase |
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may have a role in the regulation of cellular responses to hypoxia |
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demethylase that oxidatively reverses N(6)-methyladenosine (m(6)A) in mRNA |
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2-oxoglutarate (2OG) and ferrous iron-dependent nucleic acid oxygenase (NAOX) that catalyzes the demethylation of N(6)-methyladenine in RNA |
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plays a role in spermatogenesis |
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compared with other AlkB proteins, displays several unique structural features on top of the conserved double-stranded beta-helix fold typical of this protein family |
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ALKBH1, ALKBH5, ALKBH8 and FTO act as RNA demethylases |