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FLASH GENE
Symbol CADM2 contributors: - updated : 13-10-2007
HGNC name cell adhesion molecule 2
HGNC id 29849
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three immunoglobulin-like domains of the V-set, C1-set, and I-set subclasses
  • a single trans-membrane region
  • a short cytosolic tail
  • a conserved PDZ domain
    • HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily, nectin-like family
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • functioning as adhesion molecules
  • playing an important role for mediating axon-glia contact during myelination in peripheral nerves
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS