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FLASH GENE
Symbol CADM2 contributors: - updated : 13-10-2007
HGNC name cell adhesion molecule 2
HGNC id 29849
Location 3p12.1      Physical location : 85.008.132 - 86.123.577
Synonym name
  • nectin-like protein 3
  • synaptic cell adhesion molecule 2
  • immunoglobulin superfamily, member 4D
    • Synonym symbol(s) MGC104534, NECL3, synCAM2, IGSF4D, MGC104534, MGC138341
    DNA
    TYPE functioning gene
    STRUCTURE 342.00 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Urinarybladder    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three immunoglobulin-like domains of the V-set, C1-set, and I-set subclasses
  • a single trans-membrane region
  • a short cytosolic tail
  • a conserved PDZ domain
    • HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily, nectin-like family
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • functioning as adhesion molecules
  • playing an important role for mediating axon-glia contact during myelination in peripheral nerves
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS