| basic FUNCTION
| catalyzing the cross linking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds |
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involved the later stages of cell envelope formation in the epidermis and hair follicle |
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involved in terminal differentiation processes in the epidermis and contributing also to the physical resistance and the preservation of the hair follicle structure (Thibaut 2009) |
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involved in signal transduction and, like two other TGs (TGM2 and TGM5), is able to bind and hydrolyze guanosine triphosphate (Zocchi 2007) |
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plays a key role in production of the cornified envelope during epidermal differentiation  |
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TGM2 (and possibly also TGM3, TGM7) gained vital functions which have not been fully revealed, yet |
