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FLASH GENE

Symbol

ATG9B

contributors: mct/ - updated : 13-12-2005

HGNC name	ATG9 autophagy related 9 homolog B (S. cerevisiae)
HGNC id	21899

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	overlapping, antisens
text	overlapping in antisense the NOS3 gene
STRUCTURE	12.29 kb     17 Exon(s)

text structure

is a vertebrate-specific gene

MAPPING

cloned

Y

linked

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_173681 17 - 4577 NP_775952 - 924 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine neuroendocrine       highly   pancreas       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

ATG9 family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

basic FUNCTION	participating in the post-transcriptional regulation of the endothelial nitric-oxide synthase (NOS3) gene through its antisense overlap
	with ATG12, ATG5, ATG2B, are autophagy-related genes, having mononucleotide repeats with seven or more nucleotides

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral somatic mutation       in gastric and colorectal cancers with microsatellite instability

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS