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FLASH GENE
Symbol ARSI contributors: mct - updated : 20-11-2018
HGNC name arylsulfatase family member I
HGNC id 32521
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Visualeye   highly Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Epithelialbarrier liningretinal pigment epithelium (RPE) highly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
Homologene
FAMILY sulfatase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,organelle,lumen
intracellular,cytoplasm,organelle,endoplasmic reticulum
intracellular,cytoplasm,organelle,lysosome
basic FUNCTION
  • may be a secreted sulfatase and may function in the extracellular space
  • function in the gene regulatory network of early development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    one calcium ion per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SPG66
    Susceptibility
    Variant & Polymorphism
    Candidate gene candidate gene causing inherited eye diseases
    Marker
    Therapy target
    ANIMAL & CELL MODELS