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FLASH GENE
Symbol DND1 contributors: mct - updated : 11-07-2011
HGNC name dead end homolog 1 (zebrafish)
HGNC id 23799
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to testicular germ cell tumors (rare variant)
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • homozygous nonsense mutation (Ter) in murine Dnd1 (Dnd1(Ter/Ter)) results in a significant early loss of primordial germ cells (PGCs) prior to colonization of the gonad in both sexes