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FLASH GENE

Symbol

CLEC4A

contributors: SGE/npt - updated : 23-03-2010

HGNC name	C-type lectin domain family 4, member A
HGNC id	13257

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism SNP	polymorphism is associated with rheumatoid arthritis (Ronninger 2008, Lorentzen 2007)

Candidate gene
Marker
Therapy target	targeting CLEC4A can modulate plasmacytoid dendritic cell function and may be applied in disease prevention and treatment, inhibiting IFN-alpha production (Meyer-Wentrup 2008)

ANIMAL & CELL MODELS