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FLASH GENE
Symbol CNGA3 contributors: mct/npt/shn/pgu - updated : 21-06-2016
HGNC name cyclic nucleotide gated channel alpha 3
HGNC id 2150
ASSOCIATED DISORDERS
corresponding disease(s) ACHM2
related resource Retinal Information Network
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
causes a complete loss of cone phototransduction
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • CNGA3(-/-) mice) exhibited an increased nociceptive behavior in models of inflammatory pain, whereas their behavior in models of acute or neuropathic pain was normal