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FLASH GENE

Symbol

REG3G

contributors: - updated : 30-05-2006

HGNC name	regenerating islet-derived 3 gamma
HGNC id	29595

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	2p12      Physical location : 79.252.825 - 79.255.630
Synonym name	pancreatitis-associated protein 1B
Synonym symbol(s)	PAP1B, PAPIB, REG-III, UNQ429

DNA

TYPE	functioning gene
SPECIAL FEATURE
text	REG gene family is constituted from an ancestor gene by gene duplication and forms a gene cluster on the region
STRUCTURE	2.00 kb     6 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

Map	pter - REG3G - REG1B - REG1A - REGL - PAP - cen
Authors	Nata (04)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - splicing 947 19.3 175 - Nata encoding the same protein than variant 2 variant 2 - splicing 847 19.3 175 - Nata differing in the 5' UTR compared to variant 1 encoding the same protein than variant 1

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon   moderately   pancreas exocrine       highly   stomach       moderately Reproductive male system testis     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a C-type lectin domain

HOMOLOGY

interspecies	ortholog to rattus Reg3a
	ortholog to murine Reg3a
	ortholog to dog pap

Homologene

FAMILY

CATEGORY

immunity/defense , regulatory

SUBCELLULAR LOCALIZATION	extracellular
text	secreted

basic FUNCTION

might be a stress protein involved in the control of bacterial proliferation

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

inflammation

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	other,
	sugar

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS