Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

GFPT1

contributors: mct/npt/pgu - updated : 02-02-2022

HGNC name	glutamine-fructose-6-phosphate transaminase 1
HGNC id	4241

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CMSTA1

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in pancreatic cancer samples compared to peri-tumor tissues, and positively associated with lymph node metastasis, pTNM stage and shorter overall survival (OS)

Susceptibility

to insulin resistance of non-insulin dependent diabetes mellitus (minor role) to diabetic nephropathy

Variant & Polymorphism SNP	2 SNP increasing the risk of diabetic nephropathy

Candidate gene
Marker	high GFPT1 expression is identified as an independent predictor of adverse clinical outcome in our small number of pancreatic cancer patients
Therapy target

ANIMAL & CELL MODELS