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FLASH GENE

Symbol

TGM4

contributors: mct - updated : 05-06-2019

HGNC name	transglutaminase 4 (prostate)
HGNC id	11780

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in the Prostate carcinoma compared to the benign prostatic hyperplasia (BPH)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may serve as a potential predictor of biochemical recurrence of prostate cancer
Therapy target

ANIMAL & CELL MODELS

male mice knockouts for transglutaminase IV (Tgm4) fail to form a copulatory plug