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FLASH GENE

Symbol

KRTAP5-9

contributors: npt - updated : 21-10-2009

HGNC name	keratin associated protein 5-9
HGNC id	23604

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
STRUCTURE	119.00 kb     1 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_005553 1 - 1188 NP_005544 - 169 - -

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive mouth tongue       Reproductive female system breast mammary gland     Skin/Tegument skin appendages hair

cells

System Cell Pubmed Species Stage Rna symbol Skin/Tegument hair follicle cell

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

KRTAP type 5 family

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytoskeleton,intermed filament
	intracellular,nucleus

basic FUNCTION	essential for the formation of a rigid and resistant hair shaft through their extensive disulfide
	bond cross-linking with abundant cysteine residues of hair keratins

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

interacting with hair keratins

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS