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FLASH GENE
Symbol TP53I13 contributors: - updated : 11-12-2006
HGNC name tumor protein p53 inducible protein 13
HGNC id 25102
Location 17q11      Physical location : 27.895.738 - 27.900.174
Synonym name damage stimulated cytoplasmic protein 1
Synonym symbol(s) DSCP1
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach   highly
Nervousnerve   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Trp53i13
Homologene
FAMILY
CATEGORY chaperone/stress , tumor suppressor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
text with anchoring on unknown subcellular structures
basic FUNCTION
  • stress-inducible gene in both a TP53 dependent and independent manner and that its protein product can inhibit cancer cell growth
  • play crucial roles from many biological aspects including cell cycle control, DNA repair, and apoptosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein TP53 inducible
    cell & other
    REGULATION
    induced by strong genotoxic stresses not only in TP53-maintaining cells but also in TP53-dysfunctioning cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS