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FLASH GENE
Symbol DEFB109P1 contributors: shn - updated : 04-04-2011
HGNC name defensin, beta 109, pseudogene 1
HGNC id 18090
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a consensus six-cysteine motif
    • HOMOLOGY
    Homologene
    FAMILY human beta-defensins
    CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • constitutively present in gingival keratinocytes and to be downregulated in response to Candida albicans
  • may have a role in ocular surface epithelium defense against invading pathogens
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text host defense against microbial infection
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other HBD9 expression is modulated in response to the activation of TLRs in corneal epithelial cells (
    HBD9 Expression is modulated by NOD2 in corneal epithelial cells (
    regulated by IL-1beta in corneal epithelial cells (
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS