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FLASH GENE

Symbol

TXNL4A

contributors: mct - updated : 07-01-2015

HGNC name	thioredoxin-like 4A
HGNC id	30551

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	15.68 kb     3 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_006701 3 - 1415 NP_006692 - 142 - -

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive pharynx       highly Endocrine pancreas         Lymphoid/Immune tonsils       highly Reproductive female system uterus

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

ortholog to yeast Dib1

Homologene

FAMILY

CATEGORY

RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus,nucleoplasm
text	spliceosome complex

basic FUNCTION	involved in pre-mRNA splicing, and participating in different multisubunit complexes and biological processes
	besides its function in pre-mRNA splicing, is a peptidase and has autocleavage activity

CELLULAR PROCESS

nucleotide, RNA splicing

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	PQBP1 binds to TXNL4A via a continuous 23-AAs segment within its C-terminal domain
	TXNL4A hydrophobic groove recognizes a YxxPxxVL motif in PQBP1

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

BMKS

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS