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FLASH GENE
Symbol ANKRD13C contributors: mct - updated : 18-06-2011
HGNC name ankyrin repeat domain 13C
HGNC id 25374
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ankyrin repeats and AAs 489–498 of ANKRD13C are essential for its function
    • HOMOLOGY
    interspecies ortholog to rattus LOC312746
    Homologene
    FAMILY
  • ankyrin repeat family
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    text
  • protein associated with the cytosolic side of ER membranes
  • peripheral membrane protein associated with the ER
    • basic FUNCTION
  • acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER
  • novel regulator of the biogenesis and trafficking of GPCRs through the biosynthetic pathway
  • can promote the biogenesis of GPR44 and its trafficking to the plasma membrane
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting partner for the prostaglandin D2 receptor
  • interaction between ANKRD13C and GPR44
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS