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FLASH GENE

Symbol

ANKRD13C

contributors: mct - updated : 18-06-2011

HGNC name	ankyrin repeat domain 13C
HGNC id	25374

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular vessel       predominantly Lymphoid/Immune lymph node         Nervous brain

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

ankyrin repeats and AAs 489–498 of ANKRD13C are essential for its function

HOMOLOGY

interspecies

ortholog to rattus LOC312746

Homologene

FAMILY

ankyrin repeat family

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum
text	protein associated with the cytosolic side of ER membranes
	peripheral membrane protein associated with the ER

basic FUNCTION	acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER
	novel regulator of the biogenesis and trafficking of GPCRs through the biosynthetic pathway
	can promote the biogenesis of GPR44 and its trafficking to the plasma membrane

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	interacting partner for the prostaglandin D2 receptor
	interaction between ANKRD13C and GPR44

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS