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FLASH GENE
Symbol C1QL4 contributors: mct - updated : 28-03-2022
HGNC name complement component 1, q subcomponent-like 4
HGNC id 31416
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a C1Q domain
HOMOLOGY
Homologene
FAMILY C1q/TNF family
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum
basic FUNCTION
  • C1QL1, C1QL2, C1QL3, C1QL4 proteins are secreted signaling molecules that bind to ADGRB3 and act, at least in part, to regulate synapse formation and/or maintenance
  • CQL1/Ctrp14 and C1QL4/Ctrp11 stimulate the new blood vessel growth by activation of ERK1/2 signal pathway
  • C1QL4 served as a novel acute regulator of testosterone secretion, and ADGRB3 functioned as a new receptor that is involved in steroidogenesis in Leydig cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • ADGRB3 is spatiotemporally regulated by C1QL4 and STAB2 during myoblast fusion
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS