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FLASH GENE

Symbol

PARP14

contributors: mct - updated : 30-08-2011

HGNC name	poly (ADP-ribose) polymerase family, member 14
HGNC id	29232

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function delayed B lymphomagenesis and reversed the block to B-cell maturation driven by the Myc oncogene

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer metastases   new therapeutic target for inhibition of PGI/AMF inducing tumor cell migration and invasion during metastasis allergy asthm   targeting PARP14 activity may be a potential therapy for asthma and allergy

ANIMAL & CELL MODELS