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FLASH GENE
Symbol PARP12 contributors: - updated : 03-08-2005
HGNC name poly (ADP-ribose) polymerase family, member 12
HGNC id 21919
Location 7q34      Physical location : 139.723.548 - 139.763.521
Synonym name zinc finger CCCH-type domain containing 1
Synonym symbol(s) ZC3H1, PARP-12, ZC3HDC1, FLJ22693
DNA
TYPE functioning gene
STRUCTURE 39.00 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  predominantly
Reproductivefemale systemuterus   
Urinarybladder    
 kidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three C3H1-type zinc fingers
  • one PARP catalytic domain
  • two WWE domains
    • HOMOLOGY
    interspecies ortholog to murine Zc3hdc1
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION NAD+ ADP-ribosyltransferase activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS