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FLASH GENE
Symbol CDH9 contributors: mct - updated : 15-09-2009
HGNC name cadherin 9, type 2 (T1-cadherin)
HGNC id 1768
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a large N-terminal extracellular domain with five cadherin domains
  • a single membrane-spanning domain
  • a small, highly conserved C-terminal cytoplasmic domain
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh9
    ortholog to rattus Cdh9
    Homologene
    FAMILY
  • cadherin superfamily
    • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • involved in homophilic cell adhesion
  • mediate calcium-dependent cell–cell adhesion
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorders
    Variant & Polymorphism SNP rs4307059 increasing the risk of autism spectrum disorder
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS