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FLASH GENE
Symbol ANAPC16 contributors: SGE/npt - updated : 29-05-2009
HGNC name anaphase promoting complex subunit 16
HGNC id 26976
Location 10q22.1      Physical location : 73.975.805 - 73.995.616
Synonym name
  • hypothetical protein LOC119504
  • chromosome 10 open reading frame 104
  • metabolic syndrome-associated protein
  • Synonym symbol(s) bA570G20.3, FLJ33728, C10orf104, MSAG, APC16
    DNA
    TYPE functioning gene
    STRUCTURE 19.81 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 3277 11.5 110 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
     vessel    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine D10Ertd641e
    Homologene
    FAMILY
  • APC16 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may be involved in the metabolism and/or its regulation of glucose and insulin (Cui 2009)
  • CELLULAR PROCESS protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the anaphase promoting complex/cyclosome (APC/C), associating with the rest of the complex independently of ANAPC2 and ANAPC11
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other increased by glucose and decreased by insulin concentrations higher than physiological levels (Cui 2009)
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS