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FLASH GENE
Symbol CELA2B contributors: np/ - updated : 25-07-2005
HGNC name chymotrypsin-like elastase family, member 2B
HGNC id 29995
Location 1p36.21      Physical location : 15.802.595 - 15.817.894
Synonym name
  • elastase 2B
  • pancreatic elastase IIB
  • Synonym symbol(s) MGC97052, MGC142100, MGC142102, RP11-265F14.2, ELA2B
    EC.number 3.4.21.71
    DNA
    TYPE functioning gene
    STRUCTURE 15.30 kb     8 Exon(s)
    MAPPING cloned Y linked N status
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 941 28 269 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreas   specific
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal signal peptide
  • an activation peptide
  • one peptidase S1 domain
  • isoforms Precursor of a 241aa mature enzyme
    HOMOLOGY
    Homologene
    FAMILY
  • peptidase S1 family
  • elastase subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    text secreted from the pancreas
    basic FUNCTION
  • is the major elastase in the human pancreas
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS