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FLASH GENE

Symbol

VSIG2

contributors: - updated : 25-07-2005

HGNC name	V-set and immunoglobulin domain containing 2
HGNC id	17149

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon   highly   stomach       predominantly Lymphoid/Immune lymph node       moderately Reproductive male system prostate     highly Respiratory lung       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a signal peptide
	an extracellular Ig-like V-type (immunoglobulin-like) domain
	an Ig-like C2-type (immunoglobulin-like) domain
	a transmembrane region devoid of charged residues
	a cytoplasmic tail
	multiple N-glycosylation sites in the extracellular region
	multiple phosphorylation sites in the cytoplasmic tail

conjugated

GlycoP

HOMOLOGY

interspecies

ortholog to murine Vsig2

Homologene

FAMILY

CATEGORY

immunity/defense

SUBCELLULAR LOCALIZATION	plasma membrane
text	type I membrane protein

basic FUNCTION

invovled in antigen binding

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

antigen

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS